Green Biologics works closely with a number of academic research institutions to develop advanced technology in synthetic biology, microbial development, extraction of cellulosic sugars from non-food renewable feedstocks, and other relevant technologies for the production of renewable chemicals and advanced biofuels. Our current funded projects include:
REACTIF
This project’s aim is to develop advanced Clostridia strains for n-butanol production which demonstrate improved fermentation performance and economics at pilot scale with a woody (cellulosic) feedstock. The project is a collaboration between Green Biologics, the University of Nottingham, Georg-August-University Gottingen, and the University of Ulm, along with Weyland AS, a Norwegian company developing advanced hydrolysis technology for woody feedstocks.
HIPHOP
This project employs advanced metabolic engineering to develop superior microbes that produce butanol as the sole fermentation product. This greatly simplifies product recovery and enables the deployment of novel, extraction technology using water-immiscible ionic liquids. In this project, we will build on GBL’s proprietary high productivity fermentation process to demonstrate an advanced continuous fermentation. The project is a collaboration between Green Biologics and the University of Nottingham.
PASTA
This project aims to develp a novel bacterial host for the production of 1-butanol from renewable feedstocks. The strategy focuses on the modification of a clostridial species (Clostridium pasteurianum), leveraging its fast growth rates, robustness and high butanol tolerance, but overcoming its limited substrate range and its lower butanol yields. The project is a collaboration between Green Biologics and the University of Nottingham.
FLEX
This project aims to improve the range of inexpensive, sustainable feedstocks that can be fermented by solventogenic microbes, and aims to improve the efficiency of the fermentation process used. Current commercial processes require the use of extreme heat and harsh chemicals to convert agricultural waste material to fermentable sugars. This project will allow development of microbial strains that are able to use agricultural wastes that have undergone less intensive pre-treatment procedures to produce bio-butanol with high efficiency. The project is a collaboration with Green Biologics and the University of York.